• Genetics and molecular biology of tetrahydrobiopterin metabolism and deficiencies.
  Swiss National Science Foundation Research Grant
  Collaboration: B. Thöny
  

• In virto model for the blood-brain barrier .
  Collaboration: B. Stieger, Univesity of Zürich

• International database of tetrahydrobiopterin deficiencies BIODEF.
  Collaboration: J.L. Dhondt, Lille, France
  

• Database of mutations causing tetrahydrobiopterin deficiencies BIOMDB.
  Collaboration: B. Thöny
  

• International database of BH4-responsive HPA/PKU (BIOPKU)
  

• Research group for tetrahydrobiopterin-NO pathway at the University Hospital Zürich.
  Collaboration: G.Schoedon, A. Schaffner, Th. Lüscher, University Hospital, Zürich
  

• Worldwide screening and differential diagnosis of tetrahydrobiopterin deficiencies.
  Collaboration: multicenter study